Drugs acting on the heart: antihypertensive drugs
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چکیده
منابع مشابه
Drugs acting on the heart: heart failure and coronary insufficiency
Heart failure (HF) and coronary insufficiency are common amongst surgical and critical care patients. Both are chronic conditions interrupted by acute episodes. HF activates neurohormonal mechanisms that worsen renal and cardiac function. Acute heart failure (AHF) commonly presents with dyspnoea as a consequence of systolic and / or diastolic dysfunction. Goals of treatment are symptom relief, ...
متن کاملTHE EFFECT OF ANTIHYPERTENSIVE DRUGS IN THE SUPPRESSION OF ATHEROSCLEROSIS
The present investigation was undertaken to evaluate the effect of antihypertensive drugs on aortic atherogenesis in hypercholesterolemic rabbits. In enalapril and nifedipine treated rabbits aortic atherosclerotic plaque involvement was significantly decreased (p<0. Oland p<O. 05, respectively) as compared to the control group. However, in hydrochlorothiazide treated rabbits aortic atheroge...
متن کاملAntihypertensive Drugs
Hypertension is one of the most serious concerns of modern medical practice. It is estimated that in the United States, as many as 60 million people are hypertensive or are being treated with antihypertensive drugs. Among the growing population of elderly Americans, some 15 million have high blood pressure. The level of blood pressure in itself is not a chief concern, since individuals with hig...
متن کاملNew centrally acting antihypertensive drugs related to methyldopa and clonidine.
It has been well established that the antihypertensive drugs clonidine and methyldopa lower blood pressure by acting on postsynaptic alpha 2-adrenergic receptors within cardiovascular control centers of the brain. A number of novel agents designed as lipophilic and highly selective alpha 2-adrenergic stimulants have been synthesized and in general the pharmacological features of these agents re...
متن کاملHemodynamic and cardiac effects of centrally acting antihypertensive drugs.
The centrally acting alpha-adrenergic receptor agonist compounds have been available for treatment of hypertension for more than 25 years. Through studies of these compounds during this time, new knowledge has been made available not only on their mechanisms of antihypertensive action but also on the role of the adrenergic nervous system in essential hypertension. This discussion primarily revi...
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ژورنال
عنوان ژورنال: Anaesthesia & Intensive Care Medicine
سال: 2012
ISSN: 1472-0299
DOI: 10.1016/j.mpaic.2012.05.007